Rare Diseases Symptoms Automatic Extraction
Home
A random Abstract
Our Project
Our Team
Degos syndrome: malignant atrophic papulosis.
[malignant atrophic papulosis]
Malignant
atrophic
papulosis
is
a
rare
disorder
characterized
by
pathognomonic
cutaneous
lesions
that
have
been
associated
with
multiple
infarctive
thrombotic
lesions
of
other
viscera
,
most
notably
the
gastrointestinal
tract
and
the
central
nervous
system
.
Systemic
involvement
may
develop
from
weeks
to
years
after
the
onset
of
the
characteristic
cutaneous
lesions
or
,
rarely
,
may
precede
the
cutaneous
lesions
.
However
,
the
existence
of
patients
with
a
prolonged
,
purely
cutaneous
variant
of
this
disease
has
been
increasingly
appreciated
,
and
this
brings
into
question
the
appropriateness
of
applying
the
term
"
malignant
"
to
all
patients
who
have
the
peculiar
characteristic
cutaneous
lesions
of
malignant
atrophic
papulosis
.
Despite
half
a
century
of
sporadic
investigation
,
the
precise
cause
of
this
disease
remains
unknown
,
and
accurate
classification
of
this
entity
as
a
primary
vasculopathy
or
primary
coagulopathy
has
not
been
possible
.
Unfortunately
,
no
effective
therapy
exists
for
those
patients
in
whom
systemic
involvement
develops
.
Diseases
Validation
Diseases presenting
"most notably the gastrointestinal tract and the central nervous system"
symptom
malignant atrophic papulosis
You can validate or delete this automatically detected symptom
Validate the Symptom
Delete the Symptom