Malignant atrophic papulosis.

[malignant atrophic papulosis]

We describe a 34 -year -old woman presenting with a 1 -year history of asymptomatic , atrophic papules disseminated mainly on the trunk . The clinical features were characteristic of malignant atrophic papulosis , and the histopathologic features were confirmatory . The etiology of this rare condition , described for the first time in 1941 , remains unknown . Also the pathogenesis is still controversial . A vascular disorder has been postulated by most authors , primary inflammatory or thrombotic vascular changes as well as primary endothelial proliferation being often mentioned in the literature . In the present case , the biopsy specimen of a recent efflorescence showed these three alterations all together , making it impossible to identify conclusively the primary event . Thrombosis , being already noticed in such early lesions , is likely to be of pathogenic importance . Rheological therapy as described in the literature may therefore be the most appropriate . In the present case , the lesions came spontaneously to a standstill without drug therapy .

Diseases
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Diseases presenting "primary inflammatory or thrombotic vascular changes as well as primary endothelial proliferation being often mentioned in the literature" symptom

malignant atrophic papulosis

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