Rare Diseases Symptoms Automatic Extraction
Home
A random Abstract
Our Project
Our Team
[Malignant atrophic papulosis (Köhlmeier-Degos): diagnosis, therapy and course].
[malignant atrophic papulosis]
A
71
-
year
-old
male
patient
presented
with
malignant
atrophic
papulosis
(
Köhlmeier-
Degos
disease
)
.
He
developed
multiple
distinctive
cutaneous
lesions
.
The
histopathological
findings
showed
an
obliterated
arteriole
with
a
wedge-shaped
area
of
ulcerated
and
necrobiotic
dermis
.
Laboratory
tests
were
within
normal
limits
or
not
specific
.
Although
the
involvement
of
the
gastrointestinal
tract
and
other
organs
has
been
noted
in
approximately
60
%
of
the
reported
cases
,
in
this
patient
so
far
the
skin
seems
to
be
the
only
involved
site
.
There
is
no
proven
effective
therapy
for
Köhlmeier-
Degos
disease
.
In
our
case
treatment
with
pentoxifylline
and
aspirin
led
to
healing
of
all
skin
lesions
within
3
months
.
One
year
after
beginning
treatment
,
the
patient
showed
neither
new
cutaneous
lesions
,
nor
any
signs
of
systemic
involvement
.
The
combination
of
pentoxifylline
and
aspirin
should
be
considered
when
planning
treatment
strategies
for
malignant
atrophic
papulosis
.