Cutaneous manifestations of antiphospholipid antibody syndrome.

[malignant atrophic papulosis]

Many different cutaneous lesions or cutaneous -systemic syndromes can be the presenting sign of antiphospholipid antibody syndrome (APS ), or can develop during the course of disease . None of these conditions are specific for APS . Livedo reticularis or racemosa is commonly seen in APS , but it is one of the least specific findings . Other diseases are less commonly seen , in either their idiopathic or APS-associated form , but are more suggestive of APS . APS should be considered in patients who may appear to have idiopathic livedo reticularis with cerebrovascular accidents (Sneddon 's syndrome ), atrophie blanche , livedoid vasculitis , malignant atrophic papulosis , or anetoderma . Finally , retiform (branching , stellate ) purpura or necrosis is perhaps the most characteristic cutaneous lesion of many different cutaneous microvascular occlusion syndromes , including APS .

Diseases
Validation

Diseases presenting "necrosis is perhaps the most characteristic cutaneous lesion of many different cutaneous microvascular occlusion syndromes" symptom

malignant atrophic papulosis

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