Rare Diseases Symptoms Automatic Extraction

Post-streptococcal vasculopathy with evolution to Degos' disease.

[malignant atrophic papulosis]

Degos' disease or malignant atrophic papulosis is a rare disseminated occlusive vasculopathy affecting the skin, gastrointestinal tract, central nervous system, and less often other organ systems. The exact etiology of this vasculopathy has not been established. Infections, autoimmune disease and coagulation defects have been proposed as underlying pathogenic mechanisms, but none have been confirmed. Here, we report the clinical, radiological and histopathologic features of Degos' disease in a 41-year-old man following streptococcal throat infection. Prior postulated hypothesis as post-infectious immunologic mechanism may be further supported by this case.

Diseases presenting "autoimmune disease" symptom

  • acute rheumatic fever
  • coats disease
  • familial hypocalciuric hypercalcemia
  • familial mediterranean fever
  • harlequin ichthyosis
  • inclusion body myositis
  • kabuki syndrome
  • malignant atrophic papulosis
  • omenn syndrome
  • sneddon syndrome
  • waldenström macroglobulinemia
  • wiskott-aldrich syndrome

This symptom has already been validated