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Lung transplantation for obstructive lung diseases.
[lymphangioleiomyomatosis]
Chronic
obstructive
pulmonary
disease
(
COPD
)
represents
one
of
the
most
common
indications
for
lung
transplantation
,
accounting
for
approximately
one
third
of
all
procedures
performed
worldwide
to
date
.
Despite
this
extensive
experience
,
questions
remain
about
the
appropriate
timing
of
transplantation
in
the
natural
history
of
COPD
,
the
optimal
procedure
to
perform
,
and
the
survival
benefit
achieved
.
Less
commonly
encountered
obstructive
lung
disorders
for
which
transplantation
is
occasionally
performed
include
emphysema
due
to
α-
1
-
antitrypsin
deficiency
,
lymphangioleiomyomatosis
,
and
Langerhans
cell
histiocytosis
.
Like
COPD
,
the
application
of
transplantation
to
these
rare
disorders
also
poses
several
questions
.
This
article
explores
issues
that
arise
when
lung
transplantation
is
utilized
for
treatment
of
both
common
and
uncommon
obstructive
lung
disorders
.
Diseases
Validation
Diseases presenting
"uncommon obstructive lung disorders"
symptom
lymphangioleiomyomatosis
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