Rare Diseases Symptoms Automatic Extraction

Reversed halo sign in tuberous sclerosis complex.

[lymphangioleiomyomatosis]

We describe a reversed halo sign in a teenage girl with tuberous sclerosis complex (TSC). Lung manifestations of TSC include lung cysts corresponding to lymphangioleiomyomatosis and small nodules indicating multifocal micronodular pneumocyte hyperplasia (MMPH). However, a reversed halo sign in TSC has never been reported. The lesion was microscopically consistent with MMPH. Immunohistological findings also supported the notion that the lesion is associated with TSC.

Diseases presenting "lymphangioleiomyomatosis" symptom

  • lymphangioleiomyomatosis
  • proteus syndrome

This symptom has already been validated