Rare Diseases Symptoms Automatic Extraction
Home
A random Abstract
Our Project
Our Team
Motor recovery mechanism in a quadriplegic patient with locked-in syndrome.
[locked-in syndrome]
Locked-
in
syndrome
(
LIS
)
is
a
rare
neurologic
condition
caused
by
bilateral
pontine
lesions
.
Quadriplegia
is
one
of
the
most
serious
clinical
manifestations
in
patients
with
LIS
.
However
,
little
is
known
about
the
motor
recovery
mechanism
of
quadriplegia
in
patients
with
LIS
.
In
the
current
study
,
we
present
with
a
quadriplegic
patient
with
bilateral
pontine
infarcts
,
whose
motor
function
appeared
to
be
reorganized
into
the
peri-infarct
areas
of
the
infarcted
pons
,
as
demonstrated
by
diffusion
tensor
tractography
(
DTT
)
.
A
60
-
year
-old
was
diagnosed
as
LIS
due
to
bilateral
pontine
infarcts
6
years
ago
.
The
patient
presented
with
complete
paralysis
of
all
four
extremities
at
onset
.
After
slow
motor
recovery
,
the
patient
was
able
to
move
all
joint
muscles
against
gravity
and
demonstrated
some
fine
motor
activity
at
the
time
of
DTT
scanning
(
6
years
after
onset
)
.
Results
of
DTTs
for
the
corticospinal
tract
(
CST
)
in
both
hemispheres
showed
that
the
CSTs
originated
from
the
primary
motor
cortex
,
descended
along
the
known
CST
pathway
,
and
passed
through
lateral
areas
of
infarcts
in
the
pons
.
Therefore
,
motor
function
of
the
four
extremities
of
this
patient
appears
to
have
been
recovered
by
the
CST
,
which
passed
through
the
lateral
areas
to
the
pontine
infarcts
.
Diseases
Validation
Diseases presenting
"motor function"
symptom
adrenomyeloneuropathy
canavan disease
carcinoma of the gallbladder
classical phenylketonuria
gm1 gangliosidosis
hirschsprung disease
hydrocephalus with stenosis of the aqueduct of sylvius
krabbe disease
locked-in syndrome
You can validate or delete this automatically detected symptom
Validate the Symptom
Delete the Symptom