Rare Diseases Symptoms Automatic Extraction
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A random Abstract
Our Project
Our Team
Probing command following in patients with disorders of consciousness using a brain-computer interface.
[locked-in syndrome]
To
determine
if
brain
-computer
interfaces
(
BCIs
)
could
serve
as
supportive
tools
for
detecting
consciousness
in
patients
with
disorders
of
consciousness
by
detecting
response
to
command
and
communication
.
We
tested
a
4
-
choice
auditory
oddball
EEG-BCI
paradigm
on
16
healthy
subjects
and
18
patients
in
a
vegetative
state
/
unresponsive
wakefulness
syndrome
,
in
a
minimally
conscious
state
(
MCS
)
,
and
in
locked-
in
syndrome
(
LIS
)
.
Subjects
were
exposed
to
4
training
trials
and
10
-
12
questions
.
Thirteen
healthy
subjects
and
one
LIS
patient
were
able
to
communicate
using
the
BCI
.
Four
of
those
did
not
present
with
a
P
3
.
One
MCS
patient
showed
command
following
with
the
BCI
while
no
behavioral
response
could
be
detected
at
bedside
.
All
other
patients
did
not
show
any
response
to
command
and
could
not
communicate
with
the
BCI
.
T
he
present
study
provides
evidence
that
EEG
based
BCI
can
detect
command
following
in
patients
with
altered
states
of
consciousness
and
functional
communication
in
patients
with
locked-
in
syndrome
.
However
,
BCI
approaches
have
to
be
simplified
to
increase
sensitivity
.
For
some
patients
without
any
clinical
sign
of
consciousness
,
a
BCI
might
bear
the
potential
to
employ
a
"
yes-
no
"
spelling
device
offering
the
hope
of
functional
interactive
communication
.