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Liposarcoma in clownfish, Amphiprion ocellaris Cuvier, produced in indoor aquaculture.
[liposarcoma]
Clownfish
,
Amphiprion
ocellaris
Cuvier
,
produced
and
grown
in
an
experimental
indoor
aquaculture
facility
,
presented
with
lipomatous
tumours
.
A
total
of
14
affected
fish
were
examined
.
Based
on
the
total
number
of
fish
at
the
aquaculture
facility
at
the
time
of
outbreak
of
this
pathology
,
the
scope
of
the
incident
is
estimated
to
be
1
of
300
fish
.
The
tumours
were
characterized
by
the
presence
of
mature
adipocytes
of
variable
sizes
,
lipoblasts
and
by
an
invasive
behaviour
,
which
affected
internal
organs
,
muscle
,
central
nervous
system
and
,
in
one
case
,
an
eye
.
Detailed
macroscopic
and
histopathological
features
are
presented
.
The
suggested
diagnosis
is
that
of
a
well-differentiated
liposarcoma
,
a
diagnosis
so
far
never
applied
to
fish
.
The
limited
outbreak
of
the
neoplasm
lasted
a
few
months
in
2011
and
did
not
recur
.
Possible
factors
leading
to
this
phenomenon
,
notably
the
metastasis
,
are
discussed
.
Diseases
Validation
Diseases presenting
"central nervous system"
symptom
22q11.2 deletion syndrome
adrenomyeloneuropathy
alexander disease
aniridia
aromatase deficiency
canavan disease
child syndrome
classical phenylketonuria
congenital toxoplasmosis
cowden syndrome
cushing syndrome
cystinuria
dracunculiasis
erdheim-chester disease
fabry disease
gm1 gangliosidosis
hereditary cerebral hemorrhage with amyloidosis
hirschsprung disease
hodgkin lymphoma, classical
kabuki syndrome
kallmann syndrome
kindler syndrome
krabbe disease
lamellar ichthyosis
legionellosis
liposarcoma
malignant atrophic papulosis
monosomy 21
neonatal adrenoleukodystrophy
phenylketonuria
proteus syndrome
scrub typhus
severe combined immunodeficiency
sneddon syndrome
triple a syndrome
von hippel-lindau disease
waldenström macroglobulinemia
well-differentiated liposarcoma
wiskott-aldrich syndrome
wolf-hirschhorn syndrome
x-linked adrenoleukodystrophy
zellweger syndrome
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