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Middle lobe syndrome: a rare presentation of allergic bronchopulmonary aspergillosis.
[allergic bronchopulmonary aspergillosis]
Allergic
bronchopulmonary
aspergillosis
(
ABPA
)
is
a
disease
predominantly
seen
in
susceptible
asthmatic
subjects
,
due
to
a
hypersensitivity
phenomenon
caused
by
colonisation
of
the
airways
by
Aspergillus
species
.
Although
collapse
,
both
lobar
and
segmental
due
to
mucoid
impaction
,
is
not
uncommon
in
ABPA
,
a
middle
lobe
syndrome
(
MLS
)
secondary
to
ABPA
is
rather
an
uncommon
association
.
We
report
this
rare
and
unusual
clinical
presentation
in
a
36
-
year
-old
male
,
who
presented
for
evaluation
of
a
"
non
resolving
pneumonia
"
.
Imaging
suggested
the
presence
of
a
MLS
and
central
bronchiectasis
.
Further
investigations
revealed
that
the
patient
met
6
/
8
of
the
essential
diagnostic
criteria
for
ABPA
.
Appropriate
therapy
with
oral
corticosteroids
resulted
in
remarkable
symptomatic
improvement
.
Diseases
Validation
Diseases presenting
"unusual clinical presentation"
symptom
allergic bronchopulmonary aspergillosis
cutaneous mastocytosis
liposarcoma
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