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Allergic Bronchopulmonary Aspergillosis (ABPA)-The High Resolution Computed Tomography (HRCT) Chest Imaging Scenario.
[allergic bronchopulmonary aspergillosis]
Allergic
bronchopulmonary
aspergillosis
(
ABPA
)
is
a
progressive
disease
which
can
lead
to
recurrent
exacerbations
,
bronchiectatic
changes
and
end-
stage
fibrosis
.
Early
diagnosis
and
treatment
prevents
its
progression
and
alleviate
its
clinical
manifestations
.
High
resolution
CT
of
the
chest
has
emerged
as
a
promising
investigation
for
its
diagnosis
.
To
review
the
high
resolution
computed
tomography
(
HRCT
)
chest
manifestations
in
ABPA
patients
.
This
study
included
110
patients
with
ABPA
who
had
undergone
HRCT
of
the
chest
in
the
routine
diagnostic
workup
for
ABPA
.
The
scans
were
assessed
for
changes
in
bronchi
,
parenchyma
and
pleura
and
findings
consistent
with
ABPA
were
evaluated
.
HRCT
chest
was
normal
in
24
patients
.
86
patients
demonstrated
central
bronchiectasis
with
predilection
for
upper
and
middle
lobes
.
Centrilobular
nodules
with
or
without
linear
opacities
(
tree
in
bud
pattern
)
,
mucoceles
and
high
-attenuation
mucus
were
seen
in
86
%
,
59
%
and
36
%
patients
respectively
.
Central
bonchiectasis
combined
with
centrilobular
nodules
and
mucus
impaction
(
especially
high
attenuation
mucus
)
strongly
favour
the
diagnosis
of
ABPA
.