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Extracorporeal membrane oxygenation and severe acute respiratory distress secondary to Legionella: 10 year experience.
[legionellosis]
Legionella-associated
respiratory
failure
has
a
high
mortality
,
despite
modern
ventilation
modalities
.
Extracorporeal
membrane
oxygenation
(
ECMO
)
is
used
to
achieve
gas
exchange
independent
of
pulmonary
function
in
patients
with
severe
respiratory
failure
.
This
was
a
retrospective
review
of
the
management
and
outcome
of
patients
with
Legionella-associated
respiratory
failure
treated
with
ECMO
support
in
a
large
ECMO
center
over
the
past
10
years
.
A
retrospective
review
of
patients
with
confirmed
Legionella-associated
severe
respiratory
failure
managed
with
ECMO
support
at
a
single
center
.
Between
2000
and
2010
,
19
patients
with
severe
respiratory
failure
caused
by
Legionella
were
managed
with
ECMO
after
failure
to
respond
to
conventional
intensive
care
management
.
Median
PaO
2
/
FiO
2
ratio
was
66
and
median
pCO
2
was
60
torr
.
Sixteen
patients
(
84
%
)
survived
to
hospital
discharge
.
Extracorporeal
membrane
oxygenation
should
be
considered
in
patients
with
Legionella-associated
respiratory
failure
,
who
have
failed
conventional
ventilation
.
Diseases
Validation
Diseases presenting
"high mortality"
symptom
acute rheumatic fever
congenital diaphragmatic hernia
cushing syndrome
esophageal adenocarcinoma
focal myositis
homocystinuria without methylmalonic aciduria
legionellosis
malignant atrophic papulosis
pyomyositis
scrub typhus
systemic capillary leak syndrome
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