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Legionellosis and lung abscesses: contribution of legionella quantitative real-time PCR to an adapted followup.
[legionellosis]
We
report
a
case
of
severe
Legionnaires
'
disease
(
LD
)
complicated
by
a
lung
abscess
in
an
immunocompetent
patient
who
required
ECMO
therapy
and
thoracic
surgery
.
The
results
of
repeated
Legionella
quantitative
real-time
PCR
performed
on
both
sera
and
respiratory
samples
correlated
with
the
LD
severity
and
the
poor
clinical
outcome
.
Moreover
,
the
PCR
allowed
for
the
detection
of
Legionella
DNA
in
the
lung
abscess
specimen
,
which
was
negative
when
cultured
for
Legionella
.
This
case
report
provides
a
logical
basis
for
further
investigations
to
examine
whether
the
Legionella
quantitative
PCR
could
improve
the
assessment
of
LD
severity
and
constitute
a
prognostic
marker
.
Diseases
Validation
Diseases presenting
"which was negative when cultured for legionella"
symptom
legionellosis
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