Rare Diseases Symptoms Automatic Extraction
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Extracorporeal life support for acute respiratory distress syndrome due to severe Legionella pneumonia.
[legionellosis]
Legionella
is
a
common
cause
of
community-acquired
pneumonia
(
CAP
)
and
is
second
only
to
Pneumococcal
pneumonia
as
a
cause
of
severe
CAP
that
requires
treatment
in
an
intensive
care
unit
.
We
report
a
case
series
of
patients
with
severe
Legionella
pneumonia
who
developed
the
acute
respiratory
distress
syndrome
(
ARDS
)
,
failed
to
improve
with
mechanical
ventilation
alone
and
required
extracorporeal
life
support
(
ECLS
)
.
We
performed
a
retrospective
study
of
all
patients
treated
with
ECLS
at
our
institution
for
severe
ARDS
as
a
result
of
Legionella
pneumonia
from
1994
to
2006
.
A
total
of
twelve
patients
with
a
diagnosis
of
Legionella
pneumonia
were
treated
with
veno-
venous
(
VV
)
ECLS
over
this
time
period
.
Nine
of
these
twelve
(
75
%
)
were
successfully
treated
and
weaned
off
ECLS
and
8
patients
(
67
%
)
survived
to
hospital
discharge
.
Two
(
13
%
)
died
of
multisystem
organ
failure
,
one
patient
(
8
%
)
died
from
global
hypoxic
encephalopathy
and
one
(
8
%
)
was
weaned
from
ECLS
,
but
ultimately
died
of
liver
failure
.
Renal
failure
requiring
some
form
of
continuous
dialysis
occurred
in
seven
patients
(
58
%
)
and
the
survival
for
this
sub-set
of
patients
was
43
%
.
Extracorporeal
life
support
for
severe
ARDS
associated
with
Legionella
pneumonia
is
an
effective
treatment
option
when
mechanical
ventilation
fails
,
especially
when
introduced
early
in
the
course
.
Diseases
Validation
Diseases presenting
"pneumonia"
symptom
22q11.2 deletion syndrome
acute rheumatic fever
allergic bronchopulmonary aspergillosis
alpha-thalassemia
classical phenylketonuria
cohen syndrome
congenital diaphragmatic hernia
heparin-induced thrombocytopenia
hydrocephalus with stenosis of the aqueduct of sylvius
junctional epidermolysis bullosa
lamellar ichthyosis
legionellosis
liposarcoma
lymphangioleiomyomatosis
monosomy 21
oculocutaneous albinism
omenn syndrome
pleomorphic liposarcoma
primary effusion lymphoma
proteus syndrome
pyomyositis
scrub typhus
severe combined immunodeficiency
triple a syndrome
waldenström macroglobulinemia
wiskott-aldrich syndrome
x-linked adrenoleukodystrophy
zellweger syndrome
This symptom has already been validated
