Rare Diseases Symptoms Automatic Extraction
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Barrow-in-Furness: a large community legionellosis outbreak in the UK.
[legionellosis]
A
community
outbreak
of
legionellosis
occurred
in
Barrow-
in
-
Furness
,
Cumbria
,
during
July
and
August
2002
.
A
descriptive
study
and
active
case-finding
were
instigated
and
all
known
wet
cooling
systems
and
other
potential
sources
were
investigated
.
Genotypic
and
phenotypic
analysis
,
and
amplified
fragment
length
polymorphism
of
clinical
human
and
environmental
isolates
confirmed
the
air-conditioning
unit
of
a
council-owned
arts
and
leisure
centre
to
be
the
source
of
infection
.
Subsequent
sequence-based
typing
confirmed
this
link
.
One
hundred
and
seventy-
nine
cases
,
including
seven
deaths
[
case
fatality
rate
(
CFR
)
3
·
9
%
]
were
attributed
to
the
outbreak
.
Timely
recognition
and
management
of
the
incident
very
likely
led
to
the
low
CFR
compared
to
other
outbreaks
.
The
outbreak
highlights
the
responsibility
associated
with
managing
an
aerosol-producing
system
,
with
the
potential
to
expose
and
infect
a
large
proportion
of
the
local
population
and
the
consequent
legal
ramifications
and
human
cost
.
