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Cutaneous legionellosis: case report and review of the medical literature.
[legionellosis]
Discrete
nodules
developed
on
the
leg
of
a
27
-
year
-old
immunosuppressed
woman
after
an
allogeneic
stem
cell
transplant
.
Biopsy
and
culture
grew
Legionella
pneumophila
serogroup
8
.
On
day
7
of
azithromycin
treatment
,
respiratory
distress
and
abnormal
liver
transaminases
developed
,
and
the
patient
died
on
day
14
.
Review
of
the
medical
literature
identified
19
reports
of
Legionella
species-associated
skin
or
soft
tissue
infections
(
total
of
20
patients
,
13
with
confirmed
infection
)
.
Manifestations
of
the
13
confirmed
cases
included
erythematous
macular
rash
(
n
=
7
)
,
erythema
after
thoracentesis
(
n
=
1
)
,
abscess
formation
(
n
=
4
)
,
respiratory
symptoms
(
n
=
6
)
,
and
abnormal
chest
radiographs
(
n
=
8
)
.
Six
required
surgical
exploration
and
débridement
,
and
7
were
immunocompromised
.
Rash
and
respiratory
infection
improved
with
antibiotics
in
10
,
but
3
died
.
Immunosuppression
may
predispose
transplant
recipients
to
Legionella
infections
.
Diagnostic
biopsies
may
facilitate
appropriate
treatment
.
Diseases
Validation
Diseases presenting
"erythema"
symptom
acute rheumatic fever
cowden syndrome
cutaneous mastocytosis
epidermolysis bullosa simplex
erythropoietic protoporphyria
familial mediterranean fever
harlequin ichthyosis
inclusion body myositis
kindler syndrome
lamellar ichthyosis
legionellosis
liposarcoma
malignant atrophic papulosis
neuralgic amyotrophy
omenn syndrome
pyomyositis
thoracic outlet syndrome
This symptom has already been validated
