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Rapid improvement in digital ischemia and acral contracture in a collodion baby treated with topical tazarotene.
[lamellar ichthyosis]
Collodion
baby
is
a
rare
congenital
disorder
whereby
affected
infants
are
born
encased
in
a
thick
,
taut
,
shiny
,
translucent
membrane
.
The
majority
of
babies
with
collodion
membrane
have
associated
disorders
,
most
commonly
nonbullous
congenital
ichthyosiform
erythroderma
and
lamellar
ichthyosis
.
The
authors
report
a
case
of
collodion
baby
with
rare
complication
of
acral
contracture
,
ischemia
and
nail
dystrophy
.
Topical
treatment
with
tazarotene
0
.
1
%
gel
resulted
in
rapid
improvement
.
The
patient
developed
normal
nail
plates
and
full
motor
function
in
both
hands
and
feet
following
treatment
.
To
the
authors
'
knowledge
,
this
is
the
first
report
demonstrating
the
benefit
of
topical
tazarotene
for
management
of
this
rare
condition
in
a
neonate
.
Diseases
Validation
Diseases presenting
"full motor function in both hands and feet following treatment"
symptom
lamellar ichthyosis
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