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A report of a successfully treated case of ABPA in an HIV-infected individual.
[allergic bronchopulmonary aspergillosis]
Aspergillus
fumigatus
is
a
ubiquitous
fungus
responsible
for
a
variety
of
pulmonary
diseases
,
ranging
from
infection
of
a
pre-existing
cavity
as
in
aspergilloma
to
highly
invasive
disease
in
immunocompromised
hosts
.
Allergic
bronchopulmonary
aspergillosis
(
ABPA
)
is
a
hypersensitivity
response
mounted
against
antigens
of
A
.
fumigatus
manifesting
as
poorly
controlled
asthma
and
bronchiectasis
.
Although
ABPA
is
not
uncommon
,
occurrence
of
ABPA
in
HIV-affected
individuals
is
distinctly
rare
.
We
describe
the
occurrence
of
ABPA
in
a
35
-
year
-old
woman
with
poorly
controlled
asthma
since
childhood
and
HIV-
1
infection
of
11
 
years
duration
.
This
is
the
second
documented
case
of
ABPA
in
a
HIV-affected
individual
,
and
the
first
reported
case
to
be
successfully
managed
with
antifungal
therapy
alone
.
We
also
discuss
the
complex
management
issues
involved
in
treating
ABPA
in
HIV-affected
individuals
.
