Rare Diseases Symptoms Automatic Extraction
Home
A random Abstract
Our Project
Our Team
Clinical and microbiologic study of periodontitis associated with Kindler syndrome.
[kindler syndrome]
Little
is
known
about
the
onset
and
prevalence
of
periodontal
disease
in
patients
with
the
rare
Kindler
syndrome
,
a
genodermatological
disorder
.
This
study
investigated
the
level
of
clinical
periodontal
attachment
in
relation
to
age
and
presence
of
putative
periodontopathogenic
bacteria
in
individuals
with
Kindler
syndrome
.
Eighteen
individuals
diagnosed
with
Kindler
syndrome
and
13
control
subjects
,
aged
4
to
37
years
,
from
rural
Panama
received
a
limited
clinical
periodontal
examination
.
Subgingival
samples
were
collected
for
identification
of
putative
periodontal
pathogens
by
polymerase
chain
reaction
.
Mild
to
severe
gingivitis
was
a
common
finding
in
all
adults
of
the
study
population
.
Seventy
-
two
percent
(
13
/
18
)
of
the
Kindler
patients
and
46
%
(
6
/
13
)
of
the
control
subjects
showed
mild
to
severe
periodontal
disease
(
P
=
0
.
001
,
chi
-square
test
)
.
The
onset
of
periodontitis
was
earlier
and
the
progression
occurred
at
a
faster
rate
in
the
Kindler
group
.
There
was
a
strong
correlation
(
r
=
0
.
83
)
between
the
level
of
attachment
loss
and
age
in
the
Kindler
group
and
a
weaker
correlation
(
r
=
0
.
66
)
in
the
control
group
.
The
appearance
of
gingival
tissues
suggested
atypical
periodontitis
with
spontaneous
bleeding
and
fragile
,
often
desquamative
,
gingiva
.
In
periodontitis
patients
,
Porphyromonas
gingivallis
and
Diallster
pneumosintes
tended
to
occur
more
frequently
in
control
individuals
compared
to
those
with
Kindler
syndrome
.
In
the
Kindler
group
,
periodontitis
had
an
onset
in
early
teenage
years
and
progressed
more
rapidly
compared
to
non-
Kindler
individuals
of
the
same
geographic
and
ethnic
group
.
Clinical
and
microbiological
findings
suggest
atypical
periodontitis
in
Kindler
patients
.
We
propose
to
include
Kindler
syndrome
in
the
category
of
medical
disorders
predisposing
to
destructive
periodontal
disease
.
Diseases
Validation
Diseases presenting
"common finding in all adults of the study population"
symptom
kindler syndrome
You can validate or delete this automatically detected symptom
Validate the Symptom
Delete the Symptom