Rare Diseases Symptoms Automatic Extraction
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A random Abstract
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Junctional epidermolysis bullosa.
[junctional epidermolysis bullosa]
Epidermolysis
bullosa
(
EB
)
encompasses
a
heterogeneous
group
of
genodermatoses
,
characterized
by
fragility
and
blistering
of
the
skin
,
often
associated
with
extracutaneous
manifestations
.
The
level
of
vesiculation
within
the
skin
defines
3
major
subtypes
of
EB
:
EB
simplex
,
junctional
EB
,
and
dystrophic
EB
.
We
present
the
case
of
a
male
neonate
of
36
weeks
of
gestation
,
who
was
born
with
a
few
blisters
with
erosions
and
who
rapidly
developed
extensive
blistering
of
the
skin
.
Histopathology
revealed
subepidermal
blistering
.
Electron
microscopy
confirmed
the
cleavage
of
epidermis
from
dermis
within
the
lamina
lucida
.
Junctional
EB
was
the
diagnosis
.
The
patient
was
discharged
after
hospitalization
for
28
days
.
The
development
of
new
blisters
with
erosions
were
gradually
improved
after
AQUACEL
Ag
dressing
,
and
the
general
condition
was
much
better
than
at
admission
.
The
patient
likely
has
a
subtype
of
junctional
EB
termed
generalized
atrophic
benign
EB
that
clinically
improves
with
age
.
He
has
the
potential
to
father
children
and
has
a
normal
life
expectancy
.
