Rare Diseases Symptoms Automatic Extraction
Home
A random Abstract
Our Project
Our Team
Inflammatory myopathies.
[inclusion body myositis]
To
discuss
the
clinical
,
laboratory
,
and
histopathologic
features
and
presumed
pathogenic
mechanisms
of
the
four
major
categories
of
idiopathic
inflammatory
myopathy
,
namely
dermatomyositis
,
polymyositis
,
immune-mediated
necrotizing
myopathy
,
and
inclusion
body
myositis
.
Dermatomyositis
,
polymyositis
,
necrotizing
myopathy
,
and
inclusion
body
myositis
are
clinically
,
histologically
,
and
pathogenically
distinct
.
Polymyositis
is
a
T
cell-mediated
disorder
directed
against
muscle
fibers
.
The
pathogenesis
of
dermatomyositis
,
necrotizing
myopathy
,
and
inclusion
body
myositis
are
unknown
.
Dermatomyositis
,
polymyositis
,
and
necrotizing
myopathy
are
generally
,
but
not
always
,
responsive
to
immunosuppressive
therapy
,
in
contrast
to
inclusion
body
myositis
,
which
is
generally
refractory
to
therapy
.
The
pattern
of
muscle
weakness
,
other
clinical
features
(
eg
,
rash
,
concurrent
interstitial
lung
disease
)
,
laboratory
features
(
creatine
kinase
,
autoantibodies
)
,
and
muscle
biopsies
are
useful
in
distinguishing
subtypes
of
inflammatory
myopathy
and
in
guiding
treatment
.
More
research
is
necessary
to
unravel
the
exact
pathogenic
bases
of
these
myopathies
and
identify
better
treatments
.
Diseases
Validation
Diseases presenting
"presumed pathogenic mechanisms of the four major categories"
symptom
inclusion body myositis
You can validate or delete this automatically detected symptom
Validate the Symptom
Delete the Symptom