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[Biologic therapy in idiopathic inflammatory myopathy].
[inclusion body myositis]
The
aim
of
this
article
is
to
study
the
evidence-based
knowledge
related
to
the
use
of
biological
therapies
in
patients
diagnosed
with
idiopathic
inflammatory
myopathy
(
dermatomyositis
,
polymyositis
and
inclusion
body
myositis
)
.
In
this
review
the
leading
published
studies
related
to
the
use
of
biological
therapy
in
patients
with
myositis
are
analysed
;
mainly
those
with
high
methodological
standards
,
that
means
randomized
and
controlled
studies
.
Methodological
drawbacks
due
to
the
rarity
and
heterogeneity
of
these
complex
diseases
are
also
addressed
.
Up
to
now
is
not
possible
to
ascertain
the
biologics
as
a
recommended
therapy
in
patients
with
myositis
,
at
least
based
in
the
current
evidence-based
knowledge
,
although
it
can
not
be
neglected
as
a
therapeutic
option
in
some
clinical
situations
,
taking
into
account
the
scarce
of
effective
treatments
in
those
patients
,
especially
in
refractory
myositis
.
Future
studies
probably
will
help
to
better
define
the
role
of
biological
therapies
in
patients
with
idiopathic
inflammatory
myopathy
.
