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Redo aortic valve replacement in a patient with immunoglobulin A deficiency and hemophilia A.
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Immunoglobulin
A
(
IgA
)
deficiency
may
result
in
the
development
of
anti-
IgA
antibodies
.
Such
antibodies
may
result
in
anaphylaxis
when
patients
receive
standard
blood
products
.
Hemophilia
A
is
a
deficiency
of
clotting
factor
VIII
that
results
in
a
significant
coagulopathy
and
bleeding
in
the
perioperative
period
unless
precautions
are
taken
.
We
present
a
case
of
successful
management
of
combined
hemophilia
A
and
IgA
deficiency
in
a
patient
undergoing
repeated
sternotomy
for
aortic
valve
replacement
.
