Rare Diseases Symptoms Automatic Extraction
Home
A random Abstract
Our Project
Our Team
Severe second-trimester obstructive ventriculomegaly related to disorders of diencephalic, mesencephalic and rhombencephalic differentiation.
[hydrocephalus with stenosis of the aqueduct of sylvius]
By
review
of
a
series
of
cases
,
we
set
out
to
identify
sonographic
features
suggestive
of
an
obstructive
mechanism
in
second
-trimester
fetuses
with
ventriculomegaly
and
describe
developmental
disorders
related
to
pathological
differentiation
of
the
diencephalon
,
mesencephalon
and
rhombencephalon
that
lead
to
obstruction
of
cerebrospinal
fluid
flow
.
We
studied
retrospectively
11
fetuses
referred
for
severe
second
-trimester
ventriculomegaly
of
undetermined
origin
.
Neurosonography
was
performed
with
detailed
analysis
of
the
third
ventricle
,
thalami
,
cerebral
aqueduct
and
cerebellum
.
The
cerebral
imaging
data
were
compared
with
neuropathological
data
in
eight
patients
,
with
a
focus
on
the
level
and
etiology
of
the
obstruction
.
Parenchymal
thinning
and
reduction
of
the
pericerebral
spaces
were
highly
suggestive
of
ventriculomegaly
due
to
an
obstructive
mechanism
.
The
ventriculomegaly
was
related
to
diencephalosynapsis
(
thalamic
fusion
and
third
ventricle
atresia
)
in
five
cases
and
partial
/
complete
aqueduct
stenosis
in
six
;
it
was
associated
with
cerebellar
hypoplasia
in
six
cases
,
including
rhombencephalosynapsis
in
two
cases
.
In
nine
patients
,
disorders
of
the
diencephalon
,
mesencephalon
and
rhombencephalon
were
present
.
In
cases
of
severe
isolated
ventriculomegaly
in
which
sonographic
features
are
suggestive
of
an
obstructive
mechanism
,
close
examination
of
the
third
ventricle
,
thalami
,
aqueduct
of
Sylvius
and
cerebellum
may
reveal
pathological
differentiation
of
the
diencephalon
,
mesencephalon
or
rhombencephalon
,
often
in
combination
.
Diseases
Validation
Diseases presenting
"including rhombencephalosynapsis in two cases"
symptom
hydrocephalus with stenosis of the aqueduct of sylvius
You can validate or delete this automatically detected symptom
Validate the Symptom
Delete the Symptom
