Rare Diseases Symptoms Automatic Extraction

Anaplastic large cell lymphoma: features presenting diagnostic challenges.

[hodgkin lymphoma, classical]

Anaplastic large cell lymphoma has histopathologic features that necessitate a broad differential diagnosis. Diagnostic considerations include carcinoma, melanoma, and hematopoietic malignancies, including diffuse large B-cell lymphoma, classical Hodgkin lymphoma, myeloid sarcoma, and peripheral T-cell lymphoma, not otherwise specified. Unusual features can include subtle sinusoidal involvement, histiocytic morphology, cytokeratin expression, CD15 expression, and variant patterns of anaplastic lymphoma kinase expression. Cases with unusual morphologic or immunohistochemical findings will be presented to highlight the complexity encountered in practice.

Diseases presenting "melanoma" symptom

  • achondroplasia
  • carcinoma of the gallbladder
  • cowden syndrome
  • cutaneous mastocytosis
  • cystinuria
  • dystrophic epidermolysis bullosa
  • epidermolysis bullosa simplex
  • erdheim-chester disease
  • erythropoietic protoporphyria
  • esophageal adenocarcinoma
  • esophageal squamous cell carcinoma
  • hirschsprung disease
  • hodgkin lymphoma, classical
  • inclusion body myositis
  • lamellar ichthyosis
  • liposarcoma
  • lymphangioleiomyomatosis
  • oculocutaneous albinism
  • papillon-lefèvre syndrome
  • pleomorphic liposarcoma
  • proteus syndrome
  • severe combined immunodeficiency
  • werner syndrome
  • wiskott-aldrich syndrome

This symptom has already been validated