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Complications of total implantable access ports and efficacy of Taurolidine-citrate lock solution against catheter-related infections.
[hirschsprung disease]
Totally
,
implantable
access
ports
(
TIAPs
)
are
used
for
long
standing
venous
catheterization
.
This
study
was
designed
to
present
our
experiences
of
the
TIAPs
applications
and
efficacy
of
Taurolidine-citrate
lock
solution
(
TCLS
)
against
catheter-related
infections
.
We
evaluated
records
of
the
108
patients
implanted
with
112
TIAPs
,
which
had
been
performed
using
heparin
solution
or
TCLS
between
2005
and
2013
.
Duration
of
exposure
to
TIAPs
was
17
-
2051
days
(
median
:
411
days
)
.
The
primary
diagnoses
were
solid
tumours
(
n
=
57
)
,
lymphoma
(
n
=
23
)
,
haematologic
diseases
(
n
=
23
)
,
nephrotic
syndrome
(
n
=
4
)
,
Hirschsprung
disease
(
n
=
1
)
.
The
right
external
jugular
vein
was
most
frequently
used
vascular
access
route
(
72
.
3
%
)
.
Mechanical
complications
were
observed
in
four
cases
.
TIAPs
were
removed
due
to
remission
in
19
cases
and
infection
in
19
cases
.
Median
time
from
implantation
and
to
the
development
of
infection
was
60
days
.
Heparin
solution
had
been
used
for
care
in
33
ports
,
whereas
heparin
and
TCLS
had
been
used
in
79
ports
.
Based
on
statistical
comparison
,
use
of
TCLS
was
considered
to
be
an
important
factor
for
preventing
infection
(
P
=
0
.
03
)
.
We
consider
that
TCLS
reduces
infection
prevalence
so
TIAPs
would
be
used
more
extensively
and
effectively
to
prevent
infections
.
