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A beta-related cerebral amyloid angiopathy.
[hereditary cerebral hemorrhage with amyloidosis]
Cerebral
amyloid
angiopathy
is
due
to
beta
-protein
accumulation
in
the
vessel
walls
and
occurs
in
normal
aging
,
Alzheimer
's
disease
and
hereditary
cerebral
hemorrhage
with
amyloidosis
.
It
causes
intraparenchimal
and
subarachnoid
bleeding
with
hemosiderin
deposits
and
multiple
infarcts
presenting
with
headache
,
stroke
and
epilepsy
.
Such
lesions
may
contribute
to
cognitive
impairment
.
So
far
,
no
therapy
is
available
.
In
future
,
amyloid
in
the
vessel
wall
might
be
addressed
by
amyloid
disaggregating
drugs
and
amyloid
antibodies
.