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Do We Need Heparin Coating for Extracorporeal Membrane Oxygenation? New Concepts and Controversial Positions About Coating Surfaces of Extracorporeal Circuits.
[heparin-induced thrombocytopenia]
Blood
contact
with
surfaces
of
the
extracorporeal
circuit
provokes
the
activation
of
the
coagulation
system
.
To
improve
biocompatibility
of
the
extracorporeal
circuit
without
increasing
the
risk
of
bleeding
,
coatings
of
artificial
surfaces
were
designed
;
many
of
them
involve
the
use
of
heparin
.
Data
in
the
literature
show
that
heparin-induced
thrombocytopenia
is
a
major
issue
in
the
extracorporeal
membrane
oxygenation
scenario
,
and
no
relevant
benefits
have
been
shown
comparing
heparin
and
no
-heparin
coating
.
