Efferent and afferent evoked potentials in patients with adrenomyeloneuropathy.

[adrenomyeloneuropathy]

This paper investigates efferent and afferent conductions of the central nervous system by various evoked potentials in patients with adrenomyeloneuropathy (AMN ).Ten pure AMN patients without cerebral involvement were studied . Motor evoked potentials (MEPs ), somatosensory evoked potentials (SEPs ), auditory brainstem response (ABR ), and pattern reversal full-field visual evoked potentials (VEPs ) were recorded . For MEP recording , single -pulse or double -pulse magnetic brainstem stimulation (BST ) was also performed .Abnormal MEP was observed in all ten patients , abnormal SEP in all ten , abnormal ABR in nine , and abnormal VEP in only one . Brainstem latency was measured in three of the seven patients with central motor conduction time (CMCT ) prolongation . The cortical -brainstem conduction time was severely prolonged along the normal or mildly delayed brainstem-cervical conduction time in those three patients .The pattern of normal VEP and abnormal MEP , SEP , ABR is a clinically useful electrophysiological feature for the diagnosis . BST techniques are helpful to detect , functionally , intracranial corticospinal tract involvement , probably demyelination , in pure AMN patients .

Diseases
Validation

Diseases presenting "clinically useful electrophysiological feature for the diagnosis" symptom

adrenomyeloneuropathy

You can validate or delete this automatically detected symptom