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Repair of cicatricial ectropion in an infant with harlequin ichthyosis using engineered human skin.
[harlequin ichthyosis]
To
report
the
use
of
an
Apligraf
(
Organogenesis
,
Inc
.
,
Canton
,
Massachusetts
,
USA
)
human
skin
equivalent
for
repair
of
cicatricial
ectropion
in
a
patient
with
harlequin
ichthyosis
.
Interventional
case
report
.
A
6
-
week
-old
male
child
with
harlequin
ichthyosis
and
severe
bilateral
upper
eyelid
cicatricial
ectropion
underwent
repair
with
Apligraf
grafts
.
After
the
initial
repair
with
Apligraf
grafts
,
recurrent
bilateral
upper
eyelid
ectropion
developed
,
requiring
repeat
Apligraf
grafting
at
age
61
days
.
After
the
second
graft
,
the
eyelids
remained
well
positioned
until
the
child
's
sudden
death
from
respiratory
failure
at
age
6
months
.
Apligraf
human
skin
equivalent
facilitated
the
repair
of
cicatricial
ectropion
in
a
child
with
harlequin
ichthyosis
.
Diseases
Validation
Diseases presenting
"severe bilateral upper eyelid cicatricial ectropion underwent repair with apligraf grafts"
symptom
harlequin ichthyosis
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