Repair of cicatricial ectropion in an infant with harlequin ichthyosis using engineered human skin.

[harlequin ichthyosis]

To report the use of an Apligraf (Organogenesis , Inc ., Canton , Massachusetts , USA ) human skin equivalent for repair of cicatricial ectropion in a patient with harlequin ichthyosis .Interventional case report .A 6 -week -old male child with harlequin ichthyosis and severe bilateral upper eyelid cicatricial ectropion underwent repair with Apligraf grafts .After the initial repair with Apligraf grafts , recurrent bilateral upper eyelid ectropion developed , requiring repeat Apligraf grafting at age 61 days . After the second graft , the eyelids remained well positioned until the child 's sudden death from respiratory failure at age 6 months .Apligraf human skin equivalent facilitated the repair of cicatricial ectropion in a child with harlequin ichthyosis .