Idiopathic fibrosclerotic disorders and other inflammatory pseudotumors.

[focal myositis]

Fibroinflammatory disorders constitute heterogeneous clinical conditions whose cause and pathogenesis are largely unknown . Inflammatory pseudotumor has been applied in a generic sense to several of these disorders , which present as a mass displacing surrounding anatomic structures or leading to organ dysfunction secondary to compressive growth around the ureter (s ), common bile duct , or great vessels in the mediastinum . The fibrosclerosing disorders of retroperitoneal fibrosis , sclerosing mediastinitis , sclerosing cholangitis , orbital pseudotumor , and Riedel thyroiditis are seemingly related in a clinical sense because there are well-documented cases of patients with two or more of these conditions and reports of these disorders presenting in family members . Although the pathogenesis of the fibrosclerotic disorders has not been elucidated , autoimmunity in the context of an established collagen vascular disease or the setting of inflammatory periaortitis in retroperitoneal fibrosis has been one suggested mechanism . In the course of the diagnostic evaluation of an individual with a suspected fibrosclerotic disorder , it is imperative to exclude an underlying infection or malignancy . This caveat is especially relevant to sclerosing mediastinitis as a presentation of histoplasmosis or to retroperitoneal fibrosis secondary to a sclerosing large cell lymphoma . Sclerosing mesenteritis has some clinical and pathological overlap with the fibrosclerotic disorders , but its nosologic and pathogenetic relationship is uncertain at this time . There are several other fibroinflammatory processes , such as focal myositis , inflammatory fibroid polyp of the gastrointestinal tract , calcifying fibrous pseudotumor , and sclerosing peritonitis , which are probably unrelated to inflammatory myofibroblastic tumor or the primary fibrosclerotic disorders .

Diseases
Validation

Diseases presenting "organ dysfunction secondary to compressive growth around the ureter" symptom

focal myositis

You can validate or delete this automatically detected symptom