[Clinical significance of magnetic resonance imaging of skeletal muscles in idiopathic inflammatory myopathies of adults].

[focal myositis]

The purpose of this study was to evaluate the clinical significance of magnetic resonance imaging (MRI ) of skeletal muscles in Japanese patients with idiopathic inflammatory myopathies (IIM ). MRI was performed in 23 adult patients with IIM , including 10 with polymyositis , 12 with dermatomyositis , and 1 with focal myositis . Seven (73 %) of 11 patients with active IIM and 2 (17 %) of 12 patients with inactive IIM showed hyperintensity of T 2 -weighted images and normal intensity of T 1 -weighted images , indicating "edema -like abnormalities " (MRI findings for active myositis ). Muscle lipomatosis and fibrosis were demonstrated in four patients and 1 patient , respectively . Considerable selectivity of muscles in developing inflammatory disorders was found . In quadriceps muscles , for example , vastus muscles seemed to be more often affected in DM patients , whereas adductors were more often affected in PM patients . Serial examination of muscle MRIs was carried out in 4 patients and the findings paralleled the disease activities . The muscle MRI findings did not necessarily correlate with other findings , such as the presence of muscle weakness , elevated serum creatine kinase levels , myogenic electromyogram , or muscle biopsy findings . The muscle MRI was considered to be an additional useful tool for the diagnosis , evaluation of disease activity , and planning treatment of IIM .

Diseases
Validation

Diseases presenting "edema-like abnormalities"" symptom

focal myositis

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