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[Clinical significance of magnetic resonance imaging of skeletal muscles in idiopathic inflammatory myopathies of adults].
[focal myositis]
The
purpose
of
this
study
was
to
evaluate
the
clinical
significance
of
magnetic
resonance
imaging
(
MRI
)
of
skeletal
muscles
in
Japanese
patients
with
idiopathic
inflammatory
myopathies
(
IIM
)
.
MRI
was
performed
in
23
adult
patients
with
IIM
,
including
10
with
polymyositis
,
12
with
dermatomyositis
,
and
1
with
focal
myositis
.
Seven
(
73
%
)
of
11
patients
with
active
IIM
and
2
(
17
%
)
of
12
patients
with
inactive
IIM
showed
hyperintensity
of
T
2
-
weighted
images
and
normal
intensity
of
T
1
-
weighted
images
,
indicating
"
edema
-like
abnormalities
"
(
MRI
findings
for
active
myositis
)
.
Muscle
lipomatosis
and
fibrosis
were
demonstrated
in
four
patients
and
1
patient
,
respectively
.
Considerable
selectivity
of
muscles
in
developing
inflammatory
disorders
was
found
.
In
quadriceps
muscles
,
for
example
,
vastus
muscles
seemed
to
be
more
often
affected
in
DM
patients
,
whereas
adductors
were
more
often
affected
in
PM
patients
.
Serial
examination
of
muscle
MRIs
was
carried
out
in
4
patients
and
the
findings
paralleled
the
disease
activities
.
The
muscle
MRI
findings
did
not
necessarily
correlate
with
other
findings
,
such
as
the
presence
of
muscle
weakness
,
elevated
serum
creatine
kinase
levels
,
myogenic
electromyogram
,
or
muscle
biopsy
findings
.
The
muscle
MRI
was
considered
to
be
an
additional
useful
tool
for
the
diagnosis
,
evaluation
of
disease
activity
,
and
planning
treatment
of
IIM
.
Diseases
Validation
Diseases presenting
"muscle weakness"
symptom
alexander disease
canavan disease
coats disease
cohen syndrome
cystinuria
familial mediterranean fever
focal myositis
inclusion body myositis
neuralgic amyotrophy
pyomyositis
severe combined immunodeficiency
systemic capillary leak syndrome
thoracic outlet syndrome
triple a syndrome
von hippel-lindau disease
This symptom has already been validated