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Fibromyalgia in patients with other rheumatic diseases: prevalence and relationship with disease activity.
[familial mediterranean fever]
Fibromyalgia
(
FM
)
is
a
syndrome
characterized
by
chronic
widespread
pain
and
the
presence
of
specific
tender
points
.
The
prevalence
of
FM
has
been
estimated
at
2
-
7
%
of
the
general
global
population
.
The
presence
of
FM
in
several
rheumatic
diseases
with
a
structural
pathology
has
been
reported
as
11
-
30
%
.
The
objectives
of
this
study
were
to
determine
the
prevalence
of
FM
and
to
evaluate
the
possible
relationship
between
FM
existence
and
disease
activity
among
rheumatic
diseases
.
The
study
group
included
835
patients--
197
rheumatoid
arthritis
(
RA
)
,
67
systemic
lupus
erythematosus
(
SLE
)
,
119
ankylosing
spondylitis
(
AS
)
,
238
osteoarthritis
(
OA
)
,
14
familial
Mediterranean
fever
(
FMF
)
,
53
Behçet
's
disease
(
BD
)
,
71
gout
,
25
Sjögren
's
syndrome
(
SS
)
,
20
vasculitis
,
29
polymyalgia
rheumatica
(
PMR
)
,
and
two
polymyositis
(
PM
)
-
-
with
or
without
FM
.
Recorded
information
included
age
,
gender
,
laboratory
parameters
,
presence
of
fatigue
,
and
disease
activity
indexes
.
The
prevalence
of
FM
in
patients
with
rheumatologic
diseases
was
found
to
be
6
.
6
%
for
RA
,
13
.
4
%
for
SLE
,
12
.
6
%
for
AS
,
10
.
1
%
for
OA
,
5
.
7
%
for
BD
,
7
.
1
%
for
FMF
,
12
%
for
SS
,
25
%
for
vasculitis
,
1
.
4
%
for
gout
,
and
6
.
9
%
for
PMR
.
One
out
of
two
patients
with
PM
was
diagnosed
with
FM
.
Some
rheumatologic
cases
(
AS
,
OA
)
with
FM
were
observed
mostly
in
female
patients
(
p
=
0
.
000
)
.
Also
,
there
were
significant
correlations
between
disease
activity
indexes
and
Fibromyalgia
Impact
Questionnaire
scores
for
most
rheumatologic
patients
(
RA
,
AS
,
OA
,
and
BD
)
(
p
<
0
.
05
;
respectively
,
r
=
0
.
6
,
0
.
95
,
0
.
887
,
and
1
)
.
Concomitant
FM
is
a
common
clinical
problem
in
rheumatologic
diseases
,
and
its
recognition
is
important
for
the
optimal
management
of
these
diseases
.
Increased
pain
,
physical
limitations
,
and
fatigue
may
be
interpreted
as
increased
activity
of
these
diseases
,
and
a
common
treatment
option
is
the
prescription
of
higher
doses
of
biologic
agents
or
corticosteroids
.
Considerations
of
the
FM
component
in
the
management
of
rheumatologic
diseases
increase
the
likelihood
of
the
success
of
the
treatment
.
Diseases
Validation
Diseases presenting
"physical limitations"
symptom
familial mediterranean fever
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