Rare Diseases Symptoms Automatic Extraction
Home
A random Abstract
Our Project
Our Team
Assessment of sleep problems in children with familial Mediterranean fever.
[familial mediterranean fever]
This
study
aimed
to
investigate
sleep
patterns
,
sleep
disturbances
and
possible
factors
that
are
associated
with
sleep
disturbances
among
children
with
familial
Mediterranean
fever
(
FMF
)
.
Fifty
-
one
patients
with
FMF
and
84
age-
and
sex-matched
healthy
controls
were
enrolled
in
the
study
.
The
patients
who
had
an
attack
during
the
last
2
weeks
were
not
included
.
Demographic
data
,
FMF
symptoms
,
disease
duration
,
dose
of
colchicine
,
disease
severity
score
,
number
of
attacks
in
the
last
year
,
MEFV
mutation
and
serum
C-
reactive
protein
(
CRP
)
levels
were
recorded
for
each
patient
.
A
Children
's
Sleep
Habits
Questionnaire
was
performed
.
The
total
sleep
scores
of
the
patients
with
FMF
were
significantly
higher
than
the
control
group
.
Total
sleep
durations
were
similar
between
FMF
patients
and
controls
.
Children
with
FMF
had
significantly
higher
scores
regarding
sleep
-onset
delay
,
sleep
anxiety
,
night
wakings
and
sleep
-disordered
breathing
when
compared
to
healthy
controls
.
There
was
a
significant
positive
correlation
between
number
of
attacks
in
the
last
year
and
sleep
onset
delay
,
night
wakings
and
sleep
disordered-breathing
.
Disease
severity
score
and
CRP
levels
were
not
associated
with
any
of
the
subscale
scores
.
The
patients
with
exertional
leg
pain
had
significantly
higher
total
sleep
scores
than
the
ones
without
.
Furthermore
,
patients
with
exertional
leg
pain
had
significantly
higher
subscale
scores
regarding
sleep
onset
delay
,
parasomnias
and
sleep
-disordered
breathing
.
This
study
showed
for
the
first
time
that
children
with
FMF
had
more
sleep
disturbances
than
their
healthy
peers
.
Higher
numbers
of
attacks
and
exertional
leg
pain
were
associated
with
poor
sleep
quality
.
In
conclusion
,
this
study
underlines
the
need
to
assess
and
manage
sleep
problems
in
children
with
FMF
.
Diseases
Validation
Diseases presenting
"parasomnias and sleep-disordered breathing"
symptom
familial mediterranean fever
You can validate or delete this automatically detected symptom
Validate the Symptom
Delete the Symptom