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Co-Existence of Familial Mediterranean Fever and Multiple Sclerosis in Two Patients.
[familial mediterranean fever]
Two
female
patients
,
aged
23
and
25
years
-old
diagnosed
with
Familial
Mediterranean
fever
(
FMF
)
were
presented
with
ataxia
and
headache
.
Multiple
sclerosis
plaques
were
detected
in
their
spinal
and
cranial
MRI
and
diagnosis
of
multiple
sclerosis
was
established
.
Genetic
analysis
demonstrated
M
694
V
mutation
(
one
homozygous
and
the
other
heterozygous
)
in
both
of
the
patients
.
Although
it
is
quite
rare
,
coexistence
of
familial
Mediterranean
fever
and
multiple
sclerosis
should
be
kept
in
the
mind
.
