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Prevalence of periodontal disease in patients with Familial Mediterranean Fever: a cohort study from central Turkey.
[familial mediterranean fever]
The
aim
of
this
study
was
to
compare
the
periodontal
status
in
patients
with
Familial
Mediterranean
Fever
(
FMF
)
and
in
those
without
this
disease
.
84
subjects
clinically
diagnosed
with
FMF
and
75
systemically
healthy
controls
,
matched
by
age
and
gender
,
were
recruited
.
All
FMF
patients
were
on
a
regular
daily
colchicine
treatment
and
during
attack-free
periods
.
Gingival
Index
(
GI
)
,
Plaque
Index
(
PI
)
,
probing
pocket
depth
(
PD
)
,
and
clinical
attachment
level
(
CAL
)
were
measured
in
all
subjects
.
To
evaluate
periodontal
disease
further
,
patients
were
stratified
into
fi
ve
groups
.
Education
information
and
smoking
habits
were
recorded
.
The
FMF
patients
and
healthy
controls
were
comparable
for
age
,
gender
,
and
smoking
status
(
P
>
.
05
)
.
The
FMF
patients
had
significantly
higher
PI
and
GI
values
and
lower
PD
and
CAL
values
than
those
of
the
control
group
(
P
<
.
05
)
.
However
,
there
was
no
significant
difference
among
all
groups
in
terms
of
periodontal
disease
severity
(
P
>
.
05
)
.
In
the
FMF
-
severe
periodontitis
group
,
higher
PI
and
GI
values
were
seen
(
P
<
.
05
)
.
However
,
there
was
no
significant
difference
between
the
FMF
-
severe
periodontitis
group
and
the
controls
with
severe
periodontitis
regarding
the
PD
and
CAL
values
(
P
>
.
05
)
.
Patients
with
FMF
using
colchicine
did
not
manifest
higher
attachment
loss
compared
to
age-
and
sex-matched
systemically
healthy
controls
.
Diseases
Validation
Diseases presenting
"severe periodontitis"
symptom
familial mediterranean fever
papillon-lefèvre syndrome
This symptom has already been validated