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Serum bone markers levels and bone mineral density in familial mediterranean Fever.
[familial mediterranean fever]
[
Purpose
]
The
aim
of
this
study
was
to
measure
bone
mineral
density
,
serum
and
urinary
bone
turnover
parameters
,
and
to
evaluate
the
influence
of
demographic
and
genetic
factors
on
these
parameters
in
FMF
patients
.
[
Subjects
and
Methods
]
Twenty
-
seven
attack-free
patients
who
were
diagnosed
with
FMF
(
in
accordance
with
Tel
Hashomer
criteria
)
were
recruited
at
outpatient
rheumatology
clinics
.
We
investigated
whether
there
were
any
differences
between
the
FMF
patients
and
a
control
group
in
terms
of
lumbar
and
femur
bone
mineral
density
(
BMD
)
,
standard
deviation
scores
(
Z
scores
and
T
scores
)
and
bone
markers
.
[
Results
]
In
terms
of
the
median
values
of
lumbar
BMD
(
p
=
0
.
21
)
,
lumbar
T
(
p
=
0
.
098
)
and
Z
(
p
=
0
.
109
)
scores
,
femoral
neck
BMD
,
femoral
T
and
Z
scores
and
total
femur
BMD
,
T
(
p
=
0
.
788
)
and
Z
scores
,
there
were
no
significant
differences
.
[
Conclusion
]
In
our
study
,
no
statistically
significant
differences
were
found
between
FMF
patients
and
a
control
group
in
terms
of
osteoporosis
.
The
25
-
OH
vitamin
D
was
found
to
be
significantly
lower
in
FMF
patients
than
in
the
control
group
.
Diseases
Validation
Diseases presenting
"deviation scores"
symptom
familial mediterranean fever
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