Massive Proteinuria and Acute Glomerulonephritis Picture in a Patient With Familial Mediterranean Fever and E148Q Mutation.

[familial mediterranean fever]

Familial Mediterranean fever (FMF ) is an inherited auto-inflammatory disorder . Secondary AA amyloidosis is the most devastating complication of FMF . Nonamyloid renal involvements have also been reported in association with FMF , including vasculitis , focal and diffuse glomerulonephritis , and IgA nephropathy . We describe a patient with FMF and E 148 Q mutation who presented with massive proteinuria , elevated serum creatinine level , and acute glomerulonephritis picture . Disease remission was achieved after treatment with corticosteroids and colchicine .

Diseases
Validation

Diseases presenting "glomerulonephritis" symptom

acute rheumatic fever

cholangiocarcinoma

familial mediterranean fever

primary hyperoxaluria type 1

scrub typhus

typhoid

This symptom has already been validated