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Intrauterine device may trigger typical attacks of familial Mediterranean fever: a case report.
[familial mediterranean fever]
Familial
Mediterranean
fever
(
FMF
)
is
an
autosomal
recessive
disorder
characterized
by
episodic
,
recurrent
,
self-
limited
attacks
of
fever
and
serositis
(
sterile
peritonitis
,
pleuritis
,
arthritis
,
etc
)
.
The
insufficiency
in
restriction
of
mild
inflammation
contributes
this
consequence
in
FMF
.
Intrauterine
devices
(
IUDs
)
have
been
widely
used
in
the
world
for
contraception
by
gynecologists
as
an
effective
and
safe
method
.
Herein
,
we
present
a
woman
with
FMF
as
the
first
case
,
whose
attacks
were
triggered
by
copper-containing
IUD
.
Our
hypothesis
in
the
present
case
was
that
sterile
mild
inflammation
in
the
uterus
caused
by
copper-containing
IUD
may
be
the
initial
source
of
systemic
inflammatory
response
.
In
our
opinion
,
clinicians
should
consider
that
the
copper-containing
IUDs
may
be
another
cause
of
FMF
attacks
in
women
using
this
contraceptive
method
.
Diseases
Validation
Diseases presenting
"limited attacks"
symptom
familial mediterranean fever
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