Familial hypocalciuric hypercalcemia in the donor and recipient of a living related donor kidney transplant.

[familial hypocalciuric hypercalcemia]

Familial hypocalciuric hypercalcemia (FHH ) is caused by heterozygous inactivation of the calcium-sensing receptor , which is notably expressed in parathyroid and kidney . FHH is characterized by asymptomatic hypercalcemia and hypophosphatemia and confers minimal , if any , morbidity . Renal transplantation in patients with FHH has not been described previously . This report describes a patient with FHH who developed end-stage renal disease from another cause and subsequently received a living related donor kidney transplant from her FHH -affected daughter . The excellent posttransplant clinical course of both recipient and donor is emphasized .