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Is there an association between ABO blood group and overall survival in patients with esophageal squamous cell carcinoma?
[esophageal squamous cell carcinoma]
The
relationship
between
ABO
blood
group
and
clinical
characteristics
had
been
studied
in
several
cancers
.
However
,
its
role
in
esophageal
cancer
(
EC
)
is
unclear
.
The
aim
of
this
study
was
to
determine
whether
ABO
blood
group
is
associated
with
overall
survival
in
patients
with
esophageal
squamous
cell
carcinoma
(
ESCC
)
.
From
2005
to
2008
,
a
retrospective
analysis
of
496
consecutive
patients
with
ESCC
was
conducted
.
The
relationship
between
ABO
blood
group
and
clinicopathologic
features
of
ESCC
was
analyzed
.
Prognostic
factors
for
overall
survival
of
ESCC
were
also
analyzed
.
The
5
-
year
overall
survival
of
ESCC
patients
with
blood
group
A
,
B
,
AB
and
O
were
47
.
8
%
,
44
.
1
%
,
43
.
2
%
,
and
38
.
4
%
,
respectively
(
P
=
0
.
165
)
.
However
,
patients
with
blood
group
non-
O
have
a
better
5
-
year
overall
survival
than
patients
with
blood
group
O
(
45
.
7
%
vs
.
38
.
4
%
;
P
=
0
.
043
)
.
Multivariate
analyses
showed
ABO
blood
group
(
O
vs
.
non-
O
;
P
=
0
.
034
)
is
an
independent
prognostic
factors
.
ABO
blood
group
is
associated
with
overall
survival
in
patients
with
ESCC
.
We
concluded
that
patients
with
blood
group
O
have
a
significantly
worse
overall
survival
than
non-
O
blood
groups
.
Diseases
Validation
Diseases presenting
"independent prognostic factors"
symptom
carcinoma of the gallbladder
cholangiocarcinoma
esophageal carcinoma
esophageal squamous cell carcinoma
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