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Is there an association between ABO blood group and overall survival in patients with esophageal squamous cell carcinoma?
[esophageal squamous cell carcinoma]
The
relationship
between
ABO
blood
group
and
clinical
characteristics
had
been
studied
in
several
cancers
.
However
,
its
role
in
esophageal
cancer
(
EC
)
is
unclear
.
The
aim
of
this
study
was
to
determine
whether
ABO
blood
group
is
associated
with
overall
survival
in
patients
with
esophageal
squamous
cell
carcinoma
(
ESCC
)
.
From
2005
to
2008
,
a
retrospective
analysis
of
496
consecutive
patients
with
ESCC
was
conducted
.
The
relationship
between
ABO
blood
group
and
clinicopathologic
features
of
ESCC
was
analyzed
.
Prognostic
factors
for
overall
survival
of
ESCC
were
also
analyzed
.
The
5
-
year
overall
survival
of
ESCC
patients
with
blood
group
A
,
B
,
AB
and
O
were
47
.
8
%
,
44
.
1
%
,
43
.
2
%
,
and
38
.
4
%
,
respectively
(
P
=
0
.
165
)
.
However
,
patients
with
blood
group
non-
O
have
a
better
5
-
year
overall
survival
than
patients
with
blood
group
O
(
45
.
7
%
vs
.
38
.
4
%
;
P
=
0
.
043
)
.
Multivariate
analyses
showed
ABO
blood
group
(
O
vs
.
non-
O
;
P
=
0
.
034
)
is
an
independent
prognostic
factors
.
ABO
blood
group
is
associated
with
overall
survival
in
patients
with
ESCC
.
We
concluded
that
patients
with
blood
group
O
have
a
significantly
worse
overall
survival
than
non-
O
blood
groups
.
Diseases
Validation
Diseases presenting
"cancer"
symptom
achondroplasia
acute rheumatic fever
adrenal incidentaloma
alpha-thalassemia
benign recurrent intrahepatic cholestasis
cadasil
canavan disease
carcinoma of the gallbladder
cholangiocarcinoma
coats disease
congenital adrenal hyperplasia
congenital diaphragmatic hernia
cowden syndrome
cushing syndrome
cutaneous mastocytosis
dedifferentiated liposarcoma
dystrophic epidermolysis bullosa
epidermolysis bullosa simplex
erdheim-chester disease
erythropoietic protoporphyria
esophageal adenocarcinoma
esophageal carcinoma
esophageal squamous cell carcinoma
familial hypocalciuric hypercalcemia
familial mediterranean fever
gm1 gangliosidosis
heparin-induced thrombocytopenia
hereditary cerebral hemorrhage with amyloidosis
hirschsprung disease
hodgkin lymphoma, classical
inclusion body myositis
junctional epidermolysis bullosa
kabuki syndrome
kallmann syndrome
kindler syndrome
lamellar ichthyosis
liposarcoma
locked-in syndrome
lymphangioleiomyomatosis
monosomy 21
neuralgic amyotrophy
oculocutaneous albinism
oligodontia
oral submucous fibrosis
papillon-lefèvre syndrome
pendred syndrome
pleomorphic liposarcoma
primary effusion lymphoma
proteus syndrome
pyomyositis
pyruvate dehydrogenase deficiency
severe combined immunodeficiency
sneddon syndrome
systemic capillary leak syndrome
triple a syndrome
von hippel-lindau disease
waldenström macroglobulinemia
well-differentiated liposarcoma
werner syndrome
wiskott-aldrich syndrome
wolf-hirschhorn syndrome
x-linked adrenoleukodystrophy
This symptom has already been validated