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Fruit Consumption Reduces the Risk of Esophageal Cancer in Yanting, People's Republic of China.
[esophageal squamous cell carcinoma]
Objective
.
This
study
aimed
to
investigate
the
contribution
of
fruit
and
family
history
to
esophageal
cancer
,
among
residents
with
abnormal
esophagus
discovered
in
screening
.
Methods
.
The
study
was
a
frequency-matched
case-control
design
in
groups
of
normal
esophagus
,
abnormal
esophagus
but
not
carcinoma
,
and
esophageal
squamous
cell
carcinoma
.
Odds
ratio
(
OR
)
was
estimated
by
unconditional
logistic
regression
.
Results
.
Fruit
intake
(
OR
=
0
.
19
,
95
%
CI
=
0
.
06
-
0
.
56
)
and
positive
family
history
of
esophageal
cancer
(
OR
=
3
.
87
,
95
%
CI
=
1
.
41
-
10
.
63
)
were
associated
with
esophageal
cancer
compared
to
individuals
with
abnormal
conditions
of
the
esophagus
.
In
individuals
who
consumed
fruits
at
least
once
per
week
,
the
OR
for
family
cancer
history
is
reduced
to
a
nonsignificant
level
(
OR
=
1
.
06
,
95
%
CI
=
0
.
07
-
15
.
91
)
.
Conclusions
.
In
the
individuals
with
abnormal
esophagus
at
screening
,
fruit
intake
was
possibly
protective
against
esophageal
cancer
,
even
in
the
ones
with
positive
family
history
.
Local
public
health
strategies
should
focus
on
the
improvement
in
fruit
intake
.
Diseases
Validation
Diseases presenting
"cancer"
symptom
achondroplasia
acute rheumatic fever
adrenal incidentaloma
alpha-thalassemia
benign recurrent intrahepatic cholestasis
cadasil
canavan disease
carcinoma of the gallbladder
cholangiocarcinoma
coats disease
congenital adrenal hyperplasia
congenital diaphragmatic hernia
cowden syndrome
cushing syndrome
cutaneous mastocytosis
dedifferentiated liposarcoma
dystrophic epidermolysis bullosa
epidermolysis bullosa simplex
erdheim-chester disease
erythropoietic protoporphyria
esophageal adenocarcinoma
esophageal carcinoma
esophageal squamous cell carcinoma
familial hypocalciuric hypercalcemia
familial mediterranean fever
gm1 gangliosidosis
heparin-induced thrombocytopenia
hereditary cerebral hemorrhage with amyloidosis
hirschsprung disease
hodgkin lymphoma, classical
inclusion body myositis
junctional epidermolysis bullosa
kabuki syndrome
kallmann syndrome
kindler syndrome
lamellar ichthyosis
liposarcoma
locked-in syndrome
lymphangioleiomyomatosis
monosomy 21
neuralgic amyotrophy
oculocutaneous albinism
oligodontia
oral submucous fibrosis
papillon-lefèvre syndrome
pendred syndrome
pleomorphic liposarcoma
primary effusion lymphoma
proteus syndrome
pyomyositis
pyruvate dehydrogenase deficiency
severe combined immunodeficiency
sneddon syndrome
systemic capillary leak syndrome
triple a syndrome
von hippel-lindau disease
waldenström macroglobulinemia
well-differentiated liposarcoma
werner syndrome
wiskott-aldrich syndrome
wolf-hirschhorn syndrome
x-linked adrenoleukodystrophy
This symptom has already been validated