Rare Diseases Symptoms Automatic Extraction
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A random Abstract
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Application of sequential (18)F-FDG PET/CT scans for concurrent chemoradiotherapy of non-surgical squamous cell esophageal carcinoma.
[esophageal carcinoma]
To
explore
the
values
of
sequential
(
18
)
F-FDG
PET
/
CT
scanning
in
patients
with
non-surgical
esophageal
squamous
cell
carcinoma
(
ESCC
)
who
received
concurrent
chemoradiotherapy
(
CCRT
)
.
Twenty
-
eight
patients
with
pathologically
confirmed
stage
I
-IV
ESCC
and
who
received
definitive
CCRT
were
prospectively
enrolled
into
this
trial
.
The
(
18
)
F-FDG
PET
/
CT
scans
were
performed
four
times
.
The
maximum
standardized
uptake
values
(
SUVmax
)
of
each
scanning
were
named
as
SUVmaxpet
1
,
SUVmaxpet
2
,
SUVmaxpet
3
,
and
SUVmaxpet
4
,
respectively
.
The
tumor
volume
with
SUV
greater
than
40
%
of
SUVmax
was
named
as
metabolic
tumor
volume
(
MTV
)
.
Follow-up
investigation
of
patients
was
performed
to
record
progression-free
survival
(
PFS
)
,
relapse-free
survival
(
RFS
)
,
and
overall
survival
time
(
OS
)
.
The
average
value
of
MTV
before
treatment
is
19
.
3
ml
.
The
average
value
of
SUVmax
at
four
time
points
was
13
.
0
±
7
.
4
,
6
.
4
±
3
.
2
,
4
.
7
±
1
.
9
,
and
3
.
4
±
1
.
8
,
respectively
.
Median
follow-up
time
was
18
.
5
months
(
range
5
-
40
)
.
There
was
statistically
significant
difference
in
ΔR
14
(
(
SUVmaxpet
1
-
SUVmaxpet
4
)
/
SUVmaxpet
1
)
.
Multivariate
Cox
regression
survival
analysis
indicated
that
the
MTV
was
an
independent
prognostic
factor
for
PFS
and
RFS
(
HR
=
1
.
13
and
1
.
14
,
respectively
)
before
treatment
.
In
CCRT
of
non-surgical
ESCC
,
MTV
before
treatment
could
independently
predict
OS
survival
.
SUVmaxpet
2
,
SUVmaxpet
3
,
and
SUVmaxpet
4
could
predict
RFS
.
Patients
with
reductions
of
SUVmaxpet
4
less
than
75
%
had
a
poor
PFS
,
RFS
,
and
OS
.
Diseases
Validation
Diseases presenting
"squamous cell carcinoma"
symptom
carcinoma of the gallbladder
child syndrome
dystrophic epidermolysis bullosa
epidermolysis bullosa simplex
esophageal adenocarcinoma
esophageal carcinoma
esophageal squamous cell carcinoma
junctional epidermolysis bullosa
kallmann syndrome
kindler syndrome
liposarcoma
monosomy 21
oculocutaneous albinism
oral submucous fibrosis
papillon-lefèvre syndrome
This symptom has already been validated