Rare Diseases Symptoms Automatic Extraction
Home
A random Abstract
Our Project
Our Team
Non-surgical treatment versus radical esophagectomy for clinical T1N0M0 esophageal carcinoma: a single-center experience.
[esophageal carcinoma]
The
role
of
non-surgical
treatments
(
NS
)
,
such
as
chemoradiotherapy
or
radiotherapy
,
for
clinical
T
1
N
0
M
0
esophageal
cancer
(
cT
1
N
0
M
0
EC
)
has
not
been
well
delineated
.
The
aim
of
this
study
was
to
evaluate
and
compare
the
feasibility
and
efficacy
of
NS
and
Surgical
treatment
(
S
)
in
cT
1
N
0
M
0
EC
patients
.
The
medical
records
of
patients
who
received
treatment
for
cT
1
N
0
M
0
EC
at
Asan
Medical
Center
between
2003
and
2012
were
retrospectively
reviewed
.
The
baseline
characteristics
,
treatment
outcomes
and
complications
,
and
survival
were
compared
.
There
were
264
S
and
20
NS
patients
with
respective
median
ages
of
69
.
5
and
63
.
0
.
The
main
histologic
finding
was
squamous
cell
carcinoma
in
both
groups
(
97
and
100
%
,
respectively
)
.
The
Eastern
Cooperative
Oncology
Group
performance
status
and
Charlson
comorbidity
index
score
were
poorer
in
the
NS
group
.
With
a
median
follow-up
of
49
.
0
months
,
37
S
patients
(
14
%
)
and
3
NS
patients
(
15
%
)
exhibited
recurrence
.
The
first
sites
of
recurrence
for
S
and
NS
patients
were
locoregional
(
21
vs
.
3
patients
)
,
distant
(
6
vs
.
0
)
,
and
both
locoregional
and
distant
(
9
vs
.
0
)
,
respectively
.
The
median
time-
to
-recurrence
could
not
be
calculated
in
either
group
(
log-rank
test
P
=
0
.
831
)
.
The
estimated
median
overall
survival
was
64
.
4
months
(
95
%
CI
37
.
2
-
91
.
6
months
)
in
the
NS
group
and
could
not
be
calculated
in
the
S
group
(
P
=
0
.
056
)
.
Non-surgical
treatments
can
be
an
effective
alternative
to
S
for
patients
with
cT
1
N
0
M
0
EC
unfit
for
radical
surgery
.
The
role
of
NS
for
early
stage
EC
needs
to
be
further
verified
with
prospective
randomized
trials
.
Diseases
Validation
Diseases presenting
"cancer"
symptom
achondroplasia
acute rheumatic fever
adrenal incidentaloma
alpha-thalassemia
benign recurrent intrahepatic cholestasis
cadasil
canavan disease
carcinoma of the gallbladder
cholangiocarcinoma
coats disease
congenital adrenal hyperplasia
congenital diaphragmatic hernia
cowden syndrome
cushing syndrome
cutaneous mastocytosis
dedifferentiated liposarcoma
dystrophic epidermolysis bullosa
epidermolysis bullosa simplex
erdheim-chester disease
erythropoietic protoporphyria
esophageal adenocarcinoma
esophageal carcinoma
esophageal squamous cell carcinoma
familial hypocalciuric hypercalcemia
familial mediterranean fever
gm1 gangliosidosis
heparin-induced thrombocytopenia
hereditary cerebral hemorrhage with amyloidosis
hirschsprung disease
hodgkin lymphoma, classical
inclusion body myositis
junctional epidermolysis bullosa
kabuki syndrome
kallmann syndrome
kindler syndrome
lamellar ichthyosis
liposarcoma
locked-in syndrome
lymphangioleiomyomatosis
monosomy 21
neuralgic amyotrophy
oculocutaneous albinism
oligodontia
oral submucous fibrosis
papillon-lefèvre syndrome
pendred syndrome
pleomorphic liposarcoma
primary effusion lymphoma
proteus syndrome
pyomyositis
pyruvate dehydrogenase deficiency
severe combined immunodeficiency
sneddon syndrome
systemic capillary leak syndrome
triple a syndrome
von hippel-lindau disease
waldenström macroglobulinemia
well-differentiated liposarcoma
werner syndrome
wiskott-aldrich syndrome
wolf-hirschhorn syndrome
x-linked adrenoleukodystrophy
This symptom has already been validated