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Current status and controversies in adrenal incidentalomas.
[adrenal incidentaloma]
Adrenal
incidentalomas
(
AI
)
are
serendipitously
discovered
lesions
during
abdominal
imaging
studies
that
need
to
be
investigated
for
evidence
of
hormonal
hypersecretion
and
/
or
malignancy
.
Because
imaging
modalities
can
reliably
identify
lesions
that
carry
a
high
risk
of
malignancy
,
we
focus
on
the
identification
of
hypersecretory
lesions
and
those
with
subclinical
activity
,
particularly
Cushing
syndrome
.
Because
diverse
diagnostic
tests
and
cut-offs
are
employed
,
the
prevalence
of
hypersecretory
AI
varies
widely
,
and
there
is
controversy
regarding
their
long
-term
sequelae
.
In
this
article
we
provide
information
regarding
current
radiological
means
to
define
the
nature
of
AI
,
and
the
most
appropriate
biochemical
tests
for
delineating
hypersecretory
states
.
We
also
discuss
the
duration
and
intensity
of
AI
follow-up
as
well
as
the
identification
of
AI
that
require
specific
therapeutic
intervention
.
Diseases
Validation
Diseases presenting
"adrenal incidentalomas"
symptom
adrenal incidentaloma
cushing syndrome
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