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Fujinon intelligent color enhancement for the diagnosis of early esophageal squamous cell carcinoma and precancerous lesion.
[esophageal carcinoma]
Esophageal
squamous
cell
carcinoma
is
a
common
malignant
tumor
in
recent
years
,
and
the
key
for
improving
the
survival
rate
is
early
diagnosis
and
treatment
.
Computed
virtual
chromoendoscopy
with
the
Fujinon
intelligent
color
enhancement
(
FICE
)
system
was
reported
to
improve
visualization
of
neoplastic
and
non-neoplastic
lesions
in
gastroscopy
and
colonoscopy
.
The
purpose
of
this
study
was
to
evaluate
the
value
of
FICE
in
the
diagnosis
of
early
esophageal
squamous
cell
carcinoma
and
precancerous
lesions
.
Two
hundred
fifty-
seven
patients
with
suspicious
lesions
of
the
esophagus
were
examined
successively
by
FICE
,
magnifying
FICE
,
Lugol
chromoendoscopy
,
and
magnifying
Lugol
chromoendoscopy
in
the
hospital
.
The
lesions
and
the
intrapapillary
capillary
loop
(
IPCL
,
microvessels
at
the
surface
of
esophageal
carcinoma
)
were
observed
and
compared
with
the
pathologic
diagnosis
that
was
regarded
as
the
golden
standard
.
The
positive
rates
of
early
esophageal
squamous
cell
carcinoma
were
92
.
6
%
and
88
.
9
%
as
examined
by
FICE
and
Lugol
chromoendoscopy
(
p
>
0
.
05
)
,
and
96
.
3
%
and
92
.
6
%
as
examined
by
magnifying
FICE
and
magnifying
Lugol
chromoendoscopy
(
p
>
0
.
05
)
,
respectively
.
The
magnifying
FICE
could
observe
the
IPCL
of
the
esophagus
clearly
.
Early
esophageal
squamous
cell
carcinoma
and
high
-grade
intraepithelial
neoplasia
were
mainly
type
IV
and
type
V
.
Low
-grade
intraepithelial
neoplasia
and
esophagitis
were
type
II
and
type
III
,
and
normal
esophagus
was
type
I
;
however
,
the
observation
of
the
IPCL
by
magnifying
Lugol
chromoendoscopy
was
not
clear
.
Fujinon
intelligent
color
enhancement
and
magnifying
FICE
are
complements
to
Lugol
chromoendoscopy
and
magnifying
Lugol
chromoendoscopy
in
the
diagnosis
of
early
esophageal
lesions
.